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Ayurveda is one of the few systems of medicine developed in ancient times that is still widely practiced in modern times. As such, it is open to the criticism that its conceptual basis is obsolete and that its contemporary practitioners have not taken account of the developments in medicine. The political debate about the place of Ayurveda in contemporary India has continued to the present, both in the public arena and in government.
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Joshi et al. reported that through acute toxicity test, Diakyur at a high dose of mg/kg p.o. Shows no toxic symptoms in the experimental animals up to 72 h; whereas subacute toxicity test reveals that this PHF is safe for long term treatment at the dose of 1600 mg/kg p.o. Their subsequent study also proved that the PHF shows hypoglycemic and antioxidant at the dose of 1600 mg/kg (p.o.).
Ayurveda is widely practiced in India, Bangladesh, Sri Lanka, and Nepal where public institutions offer formal study in the form of a Bachelor of Ayurvedic Medicine and Surgery degree. In certain parts of the world, the legal standing of practitioners is equivalent to that of conventional medicine. Several scholars have described the contemporary Indian application of Ayurvedic practice as being “biomedicalized” relative to the more “spiritualized” emphasis to practice found in variants in the West.
Ayurvedic Pharmacopoeia of India, also known as “Ayurvedic formulary of India,” provides monographs on the preparation of Ayurvedic PHF, thus aided in standardizing the preparation of Ayurvedic PHFs. Still, this would not suffice to ensure reproducibility of every batch of PHFs. Charaka samhita has stressed on the factors to be considered while selecting the starting material of the PHFs, including habitat, season in which it grows, harvesting conditions, method of storage and pharmaceutical processing. This batch to batch variation would directly affect the effectiveness and safety of the PHFs. The need to alter the dosage regimen to obtain required therapeutic effect also seems to be tedious.
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